In a High Availability (HA) SquaredUp environment, you might experience the Default App Pool crashing on one of the servers, and EventID 1000 in the Ops Manager event log.
Faulting application name: w3wp.exe, version: 10.0.14393.0, time stamp: 0x57899b8a
Faulting module name: ntdll.dll, version: 10.0.14393.3630, time stamp: 0x5e8d4386
Exception code: 0xc0000005
Fault offset: 0x000000000002ddd0
Faulting process id: 0xfe0
Faulting application start time: 0x01d63384d54ba19f
Faulting application path: c:\windows\system32\inetsrv\w3wp.exe
Faulting module path: C:\Windows\SYSTEM32\ntdll.dll
Report Id: f3a310ce-8209-47cb-9367-d14fb5bde682
Faulting package full name:
Faulting package-relative application ID:
This issue can be caused by a corrupted SCOM agent or APM component.
To fix this issue, you can repair the SCOM agent and re-install the APM component. If you do not use the APM feature, you can completely remove the APM components.
For more information see this post - Resolve issues by removing APM components in System Center 2016 Operations Manager